The TRI Principle
1. Take a biological sample (preclinical),
2. Read the circular) RNA (laboratory),
3. Issue a diagnosis and treatment advice (clinic).
Plasma: everyone has it
Step 1
Blood and plasma, the cell-free fraction, is available to everyone, is easy and harmless and contains a wealth of biological and clinical information that can be read directly from the translation code; the RNA or indirectly through the blueprint (DNA). The NIPT test is an excellent example of a non-invasive, safe and highly specific analysis of DNA in plasma. Plasma also contains platelets, a great source of clinical information.
Molecular Stethoscope
Step 2
As a molecular stethoscope, analysis of the RNA profile in blood and plasma (including platelets) provides important and early information about disease processes. In some cases even before the onset of clinical symptoms (presymptomatic). With the current advancement in molecular diagnostics, this information can be obtained quickly and reliably to determine whether a patient is or is about to become ill.
The doctor gets tools
Step 3
With this specific information derived from the RNA work order, the doctor gets better tools for the diagnosis, treatment and prevention of diseases.
When applied during pregnancy or birth, it lowers the death rates of newborns, especially in Indonesia.
